Clinical Question: COVID-19: What are the presenting symptoms, clinical course, and risk factors for mortality?
Bottom Line: Cough and fever are the most common symptoms. Differences in testing and reporting of cases limit prognostic estimations. At minimum, 80% of cases are clinically mild. Of those hospitalized in North America, ~25% will require ICU admission. Risk factors for mortality include age >65 years, co-morbidities, long-term care residents, and those with COVID-19 associated cardiac injury.
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