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TFP #261 – Antivirals for COVID-19

Clinical Question: Do treatments such as remdesivir or other anti-virals change patient outcomes in COVID-19 patients?

Bottom Line: To date, published RCTs have not demonstrated benefit of treating COVID-19 patients with remdesivir, lopinavir-ritonavir or oseltamivir.  There are signals of potential benefits from one interim analysis of remdesivir and non-statistically different results, but more research is needed. Full publication of studies and ongoing trials will help to answer this question.    

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